The phrase “game-changing” gets bandied about a lot in entrepreneurial circles. And certainly, in this era of landmark technological change, we are spoilt for choice when it comes to people and products that have changed the way we live.

We’re about to introduce you to a woman who raises that bar to life-changing. Someone who is paving the way for millions of women to have more personalized, accurate fertility care. One who has truly moved the medical sciences needle. (Pun intended).

Piraye Beim, is indeed a rare woman. A mother to two, soon-to-be three, a world-leading genetic scientist and Founder/CEO at Celmatix – the New York biotech firm putting big data through its paces with some remarkable results.

Since launching in 2009, Celmatix has released two world-first products. The first is Polaris, a cloud-based platform that uses big data to optimize the treatment of fertility patients. Its creation was what Beim refers to as a “happy accident” on the way to solving their number one goal –  building the first genetic test for reproductive health. Fertilome, the realization of that mission, was released early this year.

Today, Celmatix are well on their way to empowering an entire generation of women to proactively manage their fertility. And Piraye Beim is just getting started.

In this week's episode:

• How critical it is to your success to be a part of a shared community
• What the business of medicine is like
• The importance of understanding the story of your customers
• How Piraye settles the debate between growth and profitability
• How to find the time to be both a parent and a game-changing entrepreneur
• & much more!

This podcast episode was brought to you by Pipedrive.

Made by marketers for marketers and with over 30,000 users worldwide, Pipedrive is one of the best CRM tools in the business. Keep track of all your sales, customers, and leads with their incredibly intuitive dashboard and simple design. Don't try any other CRM tool until you've used Pipedrive first!

Before heading to San Fransisco to devote himself fully as the CEO of the wildly popular customer relationship management (CRM) tool Pipedrive, Timo Rein was a sales consultant back in his home country of Estonia. With a knack for making sales and closing deals, Rein found himself successfully working as one of the best salesmen in his country for over 12 years.

Despite loving the industry he was in, Rein knew that there was much more he could offer the world beyond just one-on-one consultation and training sessions. There had to be a way for him to apply his years of experience and distill them into a product that could help thousands of salespeople he knew must be frustrated with the exact problems he was facing.

In Rein's own words:

"We should either find a product like this, or build a product like this. We didn't find exactly what we were looking for so we decided to build it."

Leaving the company that he called home for 12 years, he began to build his very first tech product.

The product that would become known as Pipedrive struck a chord. Ever since launching in 2010, Pipedrive has grown to more than 30,000 customers who can be found on every continent on the globe, and impressively raised $9 million in its first round of funding.

Rein shows no sign of stopping as he seeks to continue to grow Pipedrive in his own impressive fashion.

In this episode you will learn:

• How to choose between building a service-based or a product-based business
• Rein's own tips on how to improve your own sales regardless of the niche
• How to find and develop your own leadership style
• What types of people you need around you to launch and grow a successful startup
• The key to continue moving quickly and efficiently as you grow
• & much more!

After being unceremoniously tossed out of the corporate world 20 years ago, Michael Stelzner took a chance and turned toward entrepreneurship. In the years that followed, Stelzner began building a reputation as an influencer with a huge network of writers and marketers.

It all culminated in 2009 when, after noticing more and more people talking about social media, he decided to run an experimental project: see if he could build a following by creating a blog with detailed articles about social media. Grabbing the name Social Media Examiner, he got to work.

His goal was simple. Instead of being one of the hundreds of bloggers already out there writing about what they didn't like about social media or simply covering the latest news in that industry, Stelzner wanted to create a blog where he would get the best writers to craft articles that would help the average person and marketer understand how to use social media.

To say that his experiment paid off would be an understatement. Social Media Examiner is one of the biggest business blogs in the world, and is widely considered the authority on all things social media.

Beyond having an incredibly successful blog, Stelzner has expanded the brand to include a top-ranking podcast and an annual event that attracts the best marketers and entrepreneurs in the world.

Seven years into his entrepreneurial journey, Stelzner helms one of the fastest-growing and most respected media companies on the planet.

His secrets to success? A powerful mixture of marketing know-how, a strong business model, and understanding how to get the most out of your network.

In this week's episode you will learn:

• How to land interviews with some of the biggest names in your industry
• The value in giving away your best stuff for free
• What it takes to become the most influential authority in your space
• How to market effectively and connect with thousands of people
• The magic behind networking and how to harness it
• & much more!

For the past 10 years, Scott Harrison has made charity his business, and he's managed to raise $250 million and bring clean drinking water in people in more than 24 countries since he began his nonprofit charity: water.

Ever since learning the majority of diseases suffered by the poor were caused by unsafe water and poor sanitation, he has made it his life's mission to bring clean drinking water to those who need it the most. It's been an amazing journey since he first started and his organization has not only affected millions of lives around the world, but he's also inspired hundreds of others to take the path of social entrepreneurship.

But in the beginning, there really weren't many social enterprises quite like charity: water.

"My advice to people is 'go find someone who's doing what you want to do and join them instead of starting something.' In my case, I just couldn't find anyone else doing what I wanted to do, doing what I had the vision for," says Harrison.

Sleeping on the floor of a friend's closet and using the living room as an office, Harrison began to build something that would offer a solution to what he considered the greatest problem facing the world. Taking it upon himself to build an organization that he could believe in, Harrison created a fresh take on how nonprofits could run and worked to rebuild trust in the power of charity.

In this week's episode you will learn:

• The art of storytelling and why it's so important for any social enterprise
• How to craft a story that everyone can relate to
• How to build and run a worldwide enterprise through nonprofit philosophies
• How to inspire and build a team of thousands of volunteers who believe in your vision
• How to build a brand that inspires
• & so much more!

This podcast episode was brought to you by Infusionsoft

Anyone looking for the gold standard in sales and marketing solutions should turn to Infusionsoft. The complete package for small businesses of all types, save yourself some time and let Infusionsoft do all the work for you by automating huge parts of your business.

Many of us have been to one of those startup events where you're divided up into teams and have to whip up a company in the span of a weekend. You make great connections and have some fun, but typically the business idea you were working on for past 48 hours is gone by the time your head hits the pillow.

But Matthew Arevalo and his new friend, and soon-to-be co-founder, realized they were onto something special. While most people went back to their daily lives, Arevalo began dedicating all of his time and energy into this new business. The result was a company called Loot Crate, a subscription service that ships a mystery box of items made for geeks by geeks.

"Subscription boxes had been around, and had existed in the past. But a lot of the focus had been on sampling. It had been on trying to get samples of products into a box and get them out to folks," says Arevalo. "Loot Crate really was the first company to work directly and say, 'We're going to put full-sized apparel, figures, collectibles, and items that pop culture fans gravitate towards and have an emotional connection to.'"

Since that fateful weekend in 2012, the fledgling startup has grown into a powerhouse company with more than 650,000 subscribers, making it the fastest-growing company in the US.

But earning such an accolade took a lot of experimenting, perseverance, and a couple of setbacks along the way, all of which Arevalo was more than happy to share with the Foundr audience.

In this week's episode, you'll learn:

• The secret to tapping into a niche and creating a true emotional connection with your audience
• What your number one focus should be in the early stage of a fast-growing startup
• Why it's important to always be looking for feedback from your customers
• How to turn failure into a learning experience
• The difference between running a physical business and a digital one
• & much more!

This podcast episode was brought to you by Fresh Desk.

Make bad customer service a thing of the past with Fresh Desk. Whether it's with their live chat feature, their easy-to-use ticketing system, or their multi-channel customer support system, treat your customer to an experience like no other and keep them coming back.